TdB Dextran sulfate sodium – DSS Colitis 葡聚糖硫酸

CAS no. 9011-18-1​
Mw : 40000 Da 50g , 100g , 500g​

TdB Consultancy AB
分類: 產品品牌:
結腸炎研究的黃金標準。炎症性腸病是一種病因不明的多因素疾病,由兩種主要亞型組成,即潰瘍性結腸炎(ulcerative colitis)和克羅恩病(Crohn’s disease)。硫酸葡聚醣(Dextran sulfate sodium, DSS)用於誘導動物的結腸炎的實驗。改變硫酸葡聚醣(Dextran sulfate sodium, DSS)的濃度或劑量的周期可以容易地誘發急性,慢性或複發性結腸炎。

什麼是硫酸葡聚醣(Dextran sulfate sodium, DSS)?

硫酸葡聚醣(Dextran sulfate sodium, DSS)是帶負電荷的硫酸化葡聚醣,分子量為40000Da。硫酸葡聚醣(Dextran sulfate sodium, DSS)廣泛用於在小鼠模型中誘導結腸炎。當硫酸葡聚醣(Dextran sulfate sodium, DSS)在飲用水中口服給藥時,誘發腸道炎症(induce colitis)。使用2%至5%的濃度,在一周內出現症狀。

normal tissue正常的老鼠腸組織​
tissue with dss使用DSS誘導的腸組織​
使用3% DSS於飲用水中,作用7天。​

如果您需要更大量的硫酸葡聚醣(Dextran sulfate sodium, DSS),請立即聯絡我們取得報價。


TdB Consultancy 自從1980年就開始銷售DSS,有豐富的製作技術,產品也廣泛的使用在許多結腸炎研究中。



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