Biocrates Bile Acids Kit

Bile Acids Kit 採用質譜儀定量,結果可重複性有助於進階研究。包括4種分類(Primary Bile Acids, Secondary Bile Acids, Conjugated Primary Bile Acids, Conjugated Secondary Bile Acids),可同時分析16種人類特有膽汁酸,19種老鼠特有膽汁酸。只需10ul樣品即可分析,再現性高。

原廠介紹

Bile Acids Kit 採用質譜儀(Mass spectrometer)定量,結果可重複性有助於進階研究。包括4種分類(Primary bile acids 、 Primary conjugated bile acids 、 Secondary unconjugated bile acids 、 Secondary conjugated bile acids ),可同時分析16種人類特有膽汁酸(Bile acids),19種老鼠特有膽汁酸(Bile acids)。只需10ul樣品即可分析,再現性高。

  • 最早發行可定量膽汁酸(Bile acids)的試劑
  • 可偵測初級和次級膽汁酸(Bile acids)
  • 可偵測不同結構膽汁酸(Bile acids)
  • 只需10ul~20ul 樣品(血漿/血清)
  • 高通量檢測
  • 檢測結果準確且可重複性
  • 相關應用領域,癌症(Cancer),心血管疾病(Cardiovascular diseases),糖尿病(Diabetes),神經學(Neuroscience)。

Bile Acids Kit 優勢

圖: Accuracy (A) and reproducibility (B) of Biocrates® Bile Acids Kit across 12 laboratories (adapted from Pham et al., 2016)

提供全面性的訊息-20個膽汁酸

  • 5個主要膽汁酸 : 由肝臟產生
  • 5個共軛膽汁酸 : 由肝臟酵素轉化初級膽汁酸
  • 4個次級非共軛膽汁酸 :由腸道細菌轉化初級膽酸
  • 6個次級非共軛膽汁酸 :由腸道細菌和肝臟酵素轉化次級膽汁酸

高通量檢測

  • 一個星期可以檢測高達400個樣品

檢測結果準確且可重複性

  • 高度正確性與不同實驗室結果可重複性

膽汁酸(Bile acids)列表

* Partial coelution with THDCA under UHPLC conditions, quantifi able only under HPLC conditions
** semi-quantitative for Waters Xevo™ TQ MS
■ Generally present at very low concentrations (close to or below LLOQ) in samples from healthy individuals
■ Generally present concentrations well above LLOQ in samples from healthy individuals

適合偵測的質譜儀

Waters /

  • Xevo® TQ-S UHPLC
  • Xevo® TQ-S micro UHPLC

SCIEX /

  • 4000 HPLC
  • 4500 HPLC
  • 5500 HPLC / UHPLC
  • 6500 UHPLC

Thermo Scientific /

  • TSQ Vantage UHPLC

Bile Acids Kit

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產品貨號 產品內容 產品數量
與我們連絡 Biocrates® Bile Acids Kit
9120052120868 Biocrates® Bile Acids Kit (U)HPLC Column
9120052120875 Biocrates® Bile Acids Kit (U)HPLC Precolumn
9120052120882 Biocrates® Bile Acids Kit (U)HPLC Setup Box
9120052120189 MetIDQ StatPack Module

糖尿病 Diabetes

  • Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease Mouzaki et al., 2016

肝病 Hepatology

  • A Branched-Chain Amino Acid-Related Metabolic Signature Characterizes Obese Adolescents with Non-Alcoholic Fatty Liver Disease. Goffredo et al., 2017 Nutrients
  • Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease Mouzaki et al., 2016
  • Impaired Bile Acid Homeostasis in Children with Severe Acute Malnutrition Zhang et al., 2016

營養和生活方式 Nutrition and Lifestyle

  • Impaired Bile Acid Homeostasis in Children with Severe Acute Malnutrition Zhang et al., 2016

腫瘤科學 Oncology

  • Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation Bakiri et al., 2017 Journal of Experimental Medicine

微生物 Microbiome

  • Impaired Bile Acid Homeostasis in Children with Severe Acute Malnutrition Zhang et al., 2016